Important update: Healthcare facilities
CDC has updated select ways to operate healthcare systems effectively in response to COVID-19 vaccination. Learn more
Given new evidence on the B.1.617.2 (Delta) variant, CDC has updated the guidance for fully vaccinated people. CDC recommends universal indoor masking for all teachers, staff, students, and visitors to K-12 schools, regardless of vaccination status. Children should return to full-time in-person learning in the fall with layered prevention strategies in place.
The White House announced that vaccines will be required for international travelers coming into the United States, with an effective date of November 8, 2021. For purposes of entry into the United States, vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. More information is available here.
Travel requirements to enter the United States are changing, starting November 8, 2021. More information is available here.

Future Directions and Resources

Future Directions and Resources

Evaluating and Caring for Patients with Post-COVID Conditions: Interim Guidance

Updated June 14, 2021
PAGE 8 of 8

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Future Directions

Research is underway to define the post-acute and long-term phases of COVID-19, and to distinguish health effects exclusively related to infection with SARS-CoV-2 from consequences of hospitalization, and from medical procedures and treatments required for care of people with severe disease of any etiology (e.g., post-intensive care syndrome). The natural history of SARS-CoV-2 infection and COVID-19-related illnesses is a current area of investigation, and the prevalence, type, duration, and severity of persistent symptoms following resolution of acute SARS-CoV-2 infection, as well as risk factors associated with their development, continue to be studied. CDC has also partnered with the National Institute of Health (NIH), aligning efforts within the federal government to support the RECOVER initiativeexternal icon.

Knowledge of post-COVID conditions is likely to change rapidly with ongoing research. Healthcare professionals and patients should continue to check for updates on evolving guidance for post-COVID conditions. CDC will continue to work in collaboration with federal, state, local, academic, and community partners to better understand the long-term effects of SARS-CoV-2 infection, and this guidance will be updated as new information emerges.


  • CDC COVID-19 Response’s Post-COVID Conditions Unit
  • External Post-COVID Condition Experts: Kathleen Bell MD, Jean Marie Connors MD, Jill Foster MD, Dixie Harris MD, Jonathan Himmelfarb MD, Judith James MD PhD, Nomi Levy-Carrick MD MPhil, Mitchell Miglis MD, Allison Navis MD, Jennifer Possick MD, Wendy S. Post MD MS, Peter Rowe MD, Bazak Sharon MD