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Science Briefs

COVID-19 Science Briefs provide a summary of the scientific evidence used to inform specific CDC guidance and recommendations. The Science Briefs reflect the scientific evidence, and CDC’s understanding of it, on a specific topic at the time of the Brief’s publication. Though CDC seeks to update Science Briefs when and as appropriate, given ongoing changes in scientific evidence, an individual Science Brief might not reflect CDC’s current understanding of that topic. All Science Briefs are catalogued on this Science Briefs web page as historic reference materials.
COVID-19 Community Levels
March 4, 2022
This science brief provides an overview of how CDC’s COVID-19 Community Levels framework was developed, the data sources it uses, and how jurisdictions can use the information to monitor COVID-19 Community Levels and inform public health action. A comprehensive approach to assessing COVID-19 community levels can inform decisions about layered COVID-19 prevention strategies, including vaccination and masking, with explicit goals of reducing medically significant disease and limiting strain on the healthcare system.
Updated: Transmission in Schools
December 17, 2021
Updated: Community Use of Masks
Community Use of Masks to Control the Spread of SARS-CoV-2
December 6, 2021
Updated: Transmission in Schools
Novemeber 16, 2021
Updated: Vaccines and Vaccinations
SARS-CoV-2 Infection-induced and Vaccine-induced Immunity
October 29, 2021
Updated: Vaccines and Vaccinations
COVID-19 vaccines and Protection Against Variants
September 15, 2021
Surface Transmission
SARS-CoV-2 and Surface (Fomite) Transmission for Indoor Community Environments
April 5, 2021
Updated: Underlying Medical Conditions
Scientific Evidence for Conditions that Increase Risk of Severe Illness
March 29, 2021
CDC's Science Agenda for COVID-19
Learn more about the high-level framework for planning and prioritization of COVID-19 work.