Other Analytical Methods of Interest to the Foods Program
The following are analytical laboratory methods of interest to the Foods Program, but are not currently part of the FDA Foods Program Compendium of Analytical Laboratory Methods.
Other FDA Chemical Methods of Interest
The following methods lack sufficient validation status to be included in the Chemical Analysis Manual (CAM) or any another established Foods Program methods collection (e.g., Elemental Analysis Manual). These methods may be of interest because they have been used in one-time surveys or have been selected for future validation.
Analyte |
Matrix |
Method Title |
---|---|---|
Acrylamide |
Multiple foods |
|
Benzene |
Soft drinks and beverages |
|
Ephedrine alkaloids |
Botanical and dietary supplements |
FDA's Analytical Methods for Testing of Products Believed to Contain Ephedrine Alkaloids |
Furan |
Multiple foods |
|
Perchlorate |
Fruits, vegetables, milk, low moisture foods, infant foods, and water |
Rapid Determination of Perchlorate Anion in Foods by Ion Chromatography–Tandem Mass Spectrometry |
Melamine and cyanuric acid |
Animal tissue and milk-based infant formula |
Method for Determination of Melamine and Cyanuric Acid Residues In Foods using LC-MS/MS |
Other FDA Microbiological Methods of Interest
The following microbiological methods are in use in FDA laboratories or are cited by FDA compliance programs or FDA guidance documents, but lack multi-laboratory validation status and are not included in the FDA Foods Program Compendium of Analytical Laboratory Methods: Microbiological Methods. In some cases the methods have been validated at the single laboratory level under the Foods Program Guidelines for the Validation of Analytical Methods for the Detection of Microbial Pathogens and have been used in small-scale assignments at a limited number of FDA laboratories. If these single laboratory validated methods are slated for continued use, they will undergo multi-laboratory evaluation using FDA’s guidelines, and if validated, will be included in the BAM. FDA considers the methods listed below are judged to be acceptable for their intended uses.
Analytes |
Matrix |
Method Title |
---|---|---|
Cyclospora cayetanensis |
Agriculture Water |
Dead-end Ultrafiltration for the Detection of Cyclospora cayetanensis from Agricultural Water December 2022 |
Cyclospora cayetanensis |
Fresh Produce |
Molecular Detection of Cyclospora cayetanensis in Fresh Produce Using Real-Time PCR December 2022 |
All microorganisms |
Tattoo inks |
Microbiological Methods for Testing the Sterility of Tattoo Inks October 2020 |
E. coli |
Agricultural water |
Equivalent Testing Methodologies for Agricultural Water, September 2017
|
E. coli O157:H7, Salmonella |
Sprout irrigation water, sprout samples |
|
E. coli O157:H7, Salmonella |
Sprout irrigation water, sprout samples |
Testing Methodologies for E. coli O157:H7 and Salmonella species in Spent Sprout Irrigation Water (or Sprouts), October 2015 |
Listeria spp., Listeria monocytogenes |
Environmental samples |
Testing Methodology for Listeria species or Listeria monocytogenes in Environmental Samples, October 2015 |
Listeria spp., Listeria monocytogenes |
Environmental samples |
|
Salmonella Enteritidis |
Environmental samples |
Environmental Sampling and Detection of Salmonella in Poultry Houses |
Salmonella Enteritidis |
Environmental samples |
|
Salmonella Enteritidis |
Environmental samples | Detection of Salmonella in Environmental Samples from Poultry Houses |