U.S. flag An official website of the United States government
  1. Home
  2. For Federal, State, Local, Tribal, and Territorial Officials
  3. National Integrated Food Safety System (IFSS) Programs and Initiatives
  4. Domestic Mutual Reliance
  1. National Integrated Food Safety System (IFSS) Programs and Initiatives

Domestic Mutual Reliance

Domestic Mutual Reliance (banner image)

Domestic mutual reliance is a seamless partnership that enables FDA and states with comparable regulatory public health systems, as trusted partners, to rely on, coordinate with, and leverage one another’s work, data, and actions to meet the public health goal of a safe national food supply.

The FDA works with our state partners to build and recognize high quality programs using nationally recognized regulatory program standards like Manufactured Food Regulatory Program Standards (MFRPS) and the Animal Feed Regulatory Program Standards (AFRPS). Such collaboration provides opportunities for the FDA and state partners to lay a quality foundation for sharing information and working together on regulatory services and food protection that industry and consumers can trust. 


Partnership Agreements

Map of Domestic Mutual Reliance Partnership Agreements in the USA

[View Original Size Image]

Types of Partnership Agreements

  • Domestic Mutual Reliance partnership agreements capture existing and new engagements focused on advancing collaborative activities in all areas of prevention, detection, and response. California, Florida, Minnesota, Utah, Wisconsin
  • Developmental partnership agreements advance the initial development of a domestic mutual reliance collaborative relationship. Hawaii
  • Specialized partnership agreements focus on a specific collaborative activity. Alaska, Rhode Island 

Partnership agreements help us to work toward an Integrated Food Safety System (IFSS). Partners can build a highly trained workforce, coordinate food safety inspection efforts, share data, leverage resources, focus on prevention and better respond to outbreaks. This collaboration includes:

  • Data exchange/information sharing
  • Work planning and risk prioritization/categorization, including inspection frequency mandates, and comparison and reconciliation of inventories
  • Inspection, compliance/enforcement, and corrective actions
  • Environmental assessment
  • Recall oversight and effectiveness/audit checks
  • Investigation of outbreaks and complaints
  • Sample collection and laboratory capacity, analysis, and reporting
  • Field staff training
  • Industry and consumer education
  • Organizational resources and personnel
  • Development and monitoring of key domestic mutual reliance metrics


What's New

  • The FDA, CDC, and state and local partners worked together to investigate a multistate outbreak of Listeria infections linked to Dole packaged leafy greens that sickened 18 people in 13 states. The FDA analyzed positive samples collected by Dole from harvesting and processing equipment. Results showed that the Listeria strain from the equipment matched both the strain causing the illnesses and the strain from product samples collected by the Michigan Department of Agriculture and Rural Development during the December 2021 outbreak investigation, and a routine sample collected by the Georgia Department of Agriculture prior to the investigation. Dole issued two voluntary recalls, stopped using the equipment, and temporarily halted production at two processing facilities. As of April 4, 2022, the CDC has declared the outbreak over.
  • April 2022 – A joint inspection by the FDA and the New York State Department of Agriculture and Markets resulted in the seizure and destruction of nearly 5,000 pounds of rodent-defiled food. The filth conditions had been discovered during a routine FDA inspection of a firm in Brooklyn. The FDA coordinated with the state to leverage individual authorities. Thanks to this collaboration, food deemed unfit for human consumption was prevented from distribution to consumers.
  • March 2022 – The state of Connecticut and the FDA worked closely together regarding an asparagus sample imported from Peru that was found to contain carbofuran, a potentially harmful pesticide that is not allowed at any level in asparagus. The Connecticut Division of Consumer Protection and the Connecticut Agricultural Experiment Station collected and tested the asparagus. The FDA used the state’s test results and traceback information to add the foreign processor to the FDA’s Import Alert 99-05, which subjects the firm to detention without physical examination. This sample was collected as part of the Laboratory Flexible Funding Model (LFFM) Cooperative Agreement Program.


Do you have questions or would you like more information? Please submit them to [email protected].


Back to Top