2023 FDA Omics Days - Poster Gallery

Poster Abstract Booklet

Poster Gallery

Poster PDF	Title	Authors	Contact
Omics technologies to advance the FDA’s One Health Initiative
	FDA and NIST collaboration to evaluate assays and control materials for characterizing animal biotechnology products generated by genome editing	Patricia Kiesler, NIST; Natalia Kolmakova, NIST; Sierra Miller, NIST; Ayah Shevchenko, NIST; Stella S. Lee, FDA/CVM; Alexis L. Norris, FDA/CVM; Mayumi F. Miller, FDA/CVM; Adam L. Moyer, FDA/CVM; Samantha Maragh, NIST	patricia.kiesler@nist.gov
	RIPS: routine intuitive pathogen surveillance with whole genome sequence data	Tim Muruvanda, FDA/CFSAN; Arthur Pightling; FDA/CFSAN; James Pettengill, FDA/CFSAN; Hugh Rand, FDA/CFSAN	Tim.Muruvanda@fda.hhs.gov
Genomics, transcriptomics, and metagenomics
	Evaluating Renal Pathology in Post-COVID-19 Human Autopsy Tissues	Elysia Masters, FDA/NCTR; Mallikarjun Bidarimath, FDA/NCTR; Jennifer Hanks, TPA Inc.; Vaunita Parihar, Emory University; Amy Inselman, FDA/NCTR; Jessica Hawes, FDA/NCTR; Laura Schnackenberg, FDA/NCT; Kelly Mercer, FDA/NCTR	Elysia.Masters@fda.hhs.gov
	Comparison of target amplicon sequencing using the MiSeq and GridION next generation sequencing platforms for detection of foodborne pathogens	Isha Patel, FDA/CFSAN; Mark Mammel, FDA/CFSAN; Jayanthi Gangiredla, FDA/CFSAN	Isha.Patel@fda.hhs.gov
	Characterization of Soil and Lettuce Resistomes from Harvest Through Storage in Modified Atmosphere Packaging	Taylor K.S. Richter, FDA/CFSAN; Mark K. Mammel, FDA/CFSAN; Ivan Simko, USDA/ARS; Maria T Brandl, USDA/ARS; Susan R. Leonard, FDA/CFSAN	Taylor.Richter@fda.hhs.gov
	Whole Genome Metagenomics as a Tool for Probiotics Analysis	Carmen Tartera, FDA/CFSAN; Jayanthi Gangiredla, FDA/CFSAN; Mark Mammel, FDA/CFSAN; Isha Patel, FDA/CFSAN	Carmen.Tartera@fda.hhs.gov
	Utility of miROmics for Identification of Circulating Pharmacodynamic Biomarkers of IFNβ-1a Biologics	Mai Mehanna, FDA/DARS; Lakshmi Manasa Chekka, FDA/DARS; Deepti Samarth, FDA/DARS; Erica Decker, DARS/FDA; Esraa Mohamed, FDA/DARS; Yan Guo, FDA/DARS; James L Weaver, DARS/FDA; Sarah Schrieber, OND/FDA; Jeffry Florian, FDA/DARS; Yow-Ming Wang, OCP/FDA; David Strauss, FDA/DARS; Paula Hyland, FDA/DARS	Mai.Mehanna@fda.hhs.gov
	PrecisionFDA Truth Challenge V2: Using Crowdsourcing to Benchmark Variant Calling Innovation	Ezekiel Maier, Booz Allen Hamilton; Elaine Johanson, FDA/ODT; Nathan Olson, NIST; Justin Wagner, NIST; Jennifer McDaniel, NIST; Justin Zook, NIST; Samuel Westreich, DNAnexus; Omar Serang, DNAnexus; Anish Prasanna, Booz Allen Hamilton	Adrienne.Phifer@fda.hhs.gov
	Assessment of plasmids for relating the 2020 Salmonella enterica serovar Newport onion outbreak to farms implicated by the outbreak investigation	Seth Commichaux, FDA/CFSAN; Hugh Rand, FDA/CFSAN; Kiran Javkar, University of Maryland/Department of Computer Science; Erin K. Molloy, University of Maryland/Department of Computer Science; James B. Pettengill, FDA/CFSAN; Arthur Pightling, FDA/CFSAN; Maria Hoffmann, FDA/CFSAN; Mihai Pop, University of Maryland/Department of Computer Science; Victor Jayeola, FDA/CFSAN; Steven Foley, FDA/NCTR; Yan Luo, FDA/CFSAN	Seth.Commichaux@fda.hhs.gov
	Global transcriptomic analyses of Salmonella enterica serovar Agona reveals the mechanism of survival on low moisture food	Sultana Solaiman, FDA/CFSAN; Ellie Meeks, UMD/JIFSAN; Ian Hines, FDA/CFSAN; Jie Zheng, FDA/CFSAN; Maria Hoffmann, FDA/CFSAN	Sultana.Solaiman@fda.hhs.gov
	Altered transcriptome and chromatin dynamics following short- and long-term Zika infections	Aaron Scholl, FDA/CBER; Bingjie Li, FDA/CBER; Sandip De, FDA/CBER	Aaron.Scholl@fda.hhs.gov
	Metagenomics and Targeted Capture Next Generation Sequencing to Detect and Identify Insects in Foods	Monica Pava-Ripoll, FDA/CFSAN/OFS; Mark K. Mammel, FDA/CFSAN/OARSA; Elizabeth Reed, FDA/CFSAN/ORS; Martine Ferguson, FDA/CFSAN/OAO; and Padmini Ramachandran, FDA/CFSAN/ORS	Monica.Pava-Ripoll@fda.hhs.gov
	Assessing viral variant detection algorithms to improve characterization of gene therapy products and biologics	Hiral Desai, MilliporeSigma; Yanfei Zhou, MilliporeSigma; Bradley Hassan, MilliporeSigma; Alexandra Bridgeland, MilliporeSigma; William Dolan Milliporesigma; Amber Overgard, MilliporeSigma	hiral.desai@milliporesigma.com
	Temporal changes in Shiga-Toxin producing Escherichia coli (STEC) O121 transcriptome during storage in bleached flour	Ian_Hines, FDA/CFSAN; Emily_Nguyen, UMD/JIFSAN; Ellie_Meeks, UMD/JIFSAN; Sultana_Solaiman, FDA/CFSAN; Elizabeth_Reed, FDA/CFSAN; Maria_Hoffmann, FDA/CFSAN; Jie_Zheng, FDA/CFSAN	Ian.Hines@fda.hhs.gov
Not Available	A Machine Learning Approach for Identifying Variables Associated with Risk of Developing Neutralizing Antidrug Antibodies to Factor VIII	Atul Rawal, CBER/OTP/HB; Christopher Kidchob, CBER/OTP/HB; Jiayi Ou, CBER/OTP/HB; Zuben E. Sauna, CBER/OTP/HB; Osman N. Yogurtcu, CBER/OBP ; Hong Yang, CBER/OBP	Atul.Rawal@fda.hhs.gov
Not Available	Single cell sequencing of brain sequestered CD8+ T cells during experimental cerebral malaria	Miranda S. Oakley/DETTD, CBER, FDA; Micah Phillip/ Emory University; Victoria Majam/DETTD, CBER, FDA; Hong Zheng/DETTD, CBER, FDA; Mark A. KuKuruga/DBPAP, CBER, FDA; Gregory K. Tharp/ Emory University; Sanjai Kumar/DETTD, CBER, FDA	Miranda.Oakley@fda.hhs.gov
	The Transcriptome Landscape of 3D-cultured Placental Trophoblasts Reveals Activation of TLR2 and TLR3/7 in Response to Trypanosoma cruzi	Erica Silberstein, FDA/CBER/OBRR; Charles C. Chung, FDA/HIVE, Alain Debrabant, FDA/CBER/OBRR	Erica.Silberstein@fda.hhs.gov
	Dual scRNA-Seq Analysis Reveals Rare and Uncommon Parasitized Cell Populations in Chronic L. Donovani Infection	Thalia Pacheco-Fernandez FDA/CBER/OBRR/DETTD/LEP; Konstantinos Karagiannis PCV Bioinformatics Engineering, Moderna; Sreenivas Gannavaram FDA/CBER/OBRR/DETTD/LEP; Chaitenya Verma Wexner Medical Center, The Ohio State University; Parna Bhattacharya FDA/OHTVII/CDRH; Hira L. Nakhasi FDA/CBER/OBRR/DETTD/LEP; Abhay R. Satoskar Wexner Medical Center, The Ohio State University	Thalia.PachecoFernandez@fda.hhs.gov
	CSP2: A Nextflow Pipeline for the Fast and Accurate Genetic Distance Estimation from Assembled Pathogen Genomes	Robert Literman, FDA/CFSAN/OAO; James Pettengill, FDA/CFSAN/OAO; Hugh Rand, FDA/CFSAN/OAO	Robert.Literman@fda.hhs.gov
Not Available	Analysis of Various Cryopreservation Conditions for the Storage of Induced Pluripotent Stem Cells and other Cell-based Therapies	Shweta Kotian, U.S. Food and Drug Administration (FDA); Farhad Farjood, Neural Stem Cell Institute (NSCI); Nathan Boles, Neural Stem Cell Institute (NSCI); John T. Thomas, U.S. Food and Drug Administration (FDA); Brigitte L. Arduini, Neural Stem Cell Institute (NSCI); Jeffrey Stern, Neural Stem Cell Institute (NSCI); Sally Temple, Neural Stem Cell Institute (NSCI); Malcolm Moos Jr., U.S. Food and Drug Administration (FDA)	Shweta.Kotian@fda.hhs.gov
Proteomics and metabolomics
	The Challenge of Plant Identification in Complex Mixtures: Closely Related Families, Large Proteomes, and Unsequenced Genomes	Melinda A. McFarland, FDA/CFSAN/ORS; Sara M. Handy, FDA/CFSAN/ORS; Elizabeth Hunter, FDA/CFSAN/ORS; Christine H. Parker, FDA/CFSAN/ORS; Ann M. Knolhoff, FDA/CFSAN/ORS	Melinda.McFarland@fda.hhs.gov
	Proteomic Profiling Reveals Antibiotic Resistance Mechanisms in Staphylococcus epidermidis Biofilms under Tigecycline Pressure	Kidon Sung, FDA/NCTR; Miseon Park, FDA/NCTR; Jungwhan Chon, Kyungin Women's University, Korea; Ohgew Kweon, FDA/NCTR; Saeed Khan, FDA/NCTR; Andrew Shen, FDA/NCTR; Angel Paredes, FDA/NCTR	Kidon.Sung@fda.hhs.gov
	Optimizing dia-PASEF isolation window schemes for proteomics measurements on a timsTOF ultra instrument	Ryan Marsico, Bruker Daltonics; Markus Lubeck, Bruker Daltonics; ,Stephanie Kaspar-Schoenefeld, Bruker Daltonics; Christoph Krisp, Bruker Daltonics; Andreas Schmidt, Bruker Daltonics; Florian Busch, Bruker Daltonics; Eduardo Carrascosa, Bruker Daltonics; Oliver Raether; Gary Kruppa, Bruker Daltonics	Ryan.Marsico@bruker.com
Not Available	Deeper plasma proteome coverage enables identification of novel biomarkers and classification of diseases	Shourjo Ghose, Andreas Schmidt, Zehan Hu, Claudia Martelli, Katharina Limm, Xaver Wurzenberger, Katrin Hartinger, Sebastian Mueller, Nils A. Kulak	shourjo.ghose@bruker.com
	Identifying metabolite markers for detection of flaviviruses in human induced Pluripotent Stem Cells (hiPSCs)	Tahira Fatima OTP/DCT2/TVBB; Sandip De OTP/DCT2/TVBB	Tahira.Fatima@fda.hhs.gov
	A practical lock-mass calibrant introduction method for improved mass accuracy and reduced false positive identifications in non-targeted analyses	Christine Fisher (O'Donnell), FDA/CFSAN; Shannon Murphy, FDA/CFSAN; Ann Knolhoff, FDA/CFSAN	Christine.ODonnell@fda.hhs.gov
	When is Enough Actually Enough- How Does the Number of Replicates Influence the Quality of Non-Targeted Analysis Results?	Karen Butler, FDA/CFSAN; Erica Bakota, FDA/ORA; Christine Fisher, FDA/CFSAN; Brian Ng, FDA/CFSAN; Ann Knolhoff, FDA/CFSAN	Karen.Butler@fda.hhs.gov
	Metabolomics Evaluation of the Impact of Violet-Blue Light (405 nm) on Platelet Concentrate	Chintamani D. Atreya, CBER/FDA; Jinchun Sun, FDA/NCTR; Neetu Dahiya, FDACBER, Tom Schmitt, FDA/NCTR; Caitlin Stewart, U of Strath; John Anderson; U of Strath; Scott MacGregor, U of Strath; Michelle Maclean, U of Strath; Richard. D. Beger, FDA/NCTR	Chintamani.Atreya@fda.hhs.gov
	Application of Metabolomic Analysis Towards the Discovery of Biomarkers of Immunogenecity and Efficacy of Parasitic Vaccines	Nazli Azodi, FDA/CBER/OBRR/DETTD/LEP; Hannah Markle, FDA/CBER/OBRR/DETTD/LEP; Timur Oljuskin, USDA; Parna Bhattacharya, FDA/OHTVII/CDRH; Greta Volpedo, The Ohio State University; Abhay Satoskar, The Ohio State University; Sreenivas Gannavaram, FDA/CBER/OBRR/DETTD/LEP; Hira L. Nakhasi, FDA/CBER/OBRR/DETTD/LEP	Sreenivas.Gannavaram@fda.hhs.gov
	Evaluation of plasma proteome and miRNA changes related to COVID-19 patient severity response	Beger, Richard, FDA/NCTR; Yu, Li-Rong FDA/NCTR; Han Tao, FDA/NCTR; Vijay, Vikrant, FDA/NCTR; Pence, Lisa, FDA/NCRT; Sun, Jinchun, FDA/NCTR; Bidarimath, Mallikarjun, FDA/NCTR; Schmitt, Thomas, FDA/NCTR; Mercer, Kelly, FDA/NCTR; Masters, Elysia, FDA/NCTR; Hawes, Jessica, FDA/NCTR; Smallwood, Heather, UTHSC; Arthur, John UAMS; Bhattacharya, Sudeepa, ASU; Burkhart, Keith, FDA/CDER	Richard.Beger@fda.hhs.gov
Not Available	Applying MHC-II Associated Peptide Proteomics (MAPPs) assay to study the Immunogenicity of Staphylococcus aureus Cas9	Louis Hopkins, FDA/CBER; Joseph R. McGill, FDA/CBER; Swati Mukherjee, Editas; Kate Zhang, Editas; and Zuben E. Sauna,FDA/CBER;	Vijaya.Simhadri@fda.hhs.gov
	Lipidomics Evaluation of the Impact of Fentanyl Treatments on Neural Stem Cells	Richard Beger, FDA/NCTR; Jinchun Sun, FDA/NCTR; Rohini Donakonda, FDA/NCTR; Shuliang Liu, FDA/NCTR; Fang Liu, FDA/NCTR; Cheng Wang, FDA/NCTR	Richard.Beger@fda.hhs.gov
	MSlineaR: a new tool to assess linearity, improving statistical robustness and quality assurance in untargeted metabolomics	Janine Wiebach, Metabolomics Platform, Berlin Institute of Health at Charité – Universitätsmedizin Berlin; Jennifer Kirwan, Metabolomics Platform, Berlin Institute of Health at Charité – Universitätsmedizin Berlin; Álvaro Fernández Ochoa, Department of Analytical Chemistry, Faculty of Sciences, University of Granada	Janine.wiebach@bih-charite.de
	Identification of Circulating Pharmacodynamic Biomarkers of IL-5 Inhibitors using proteomics approach	Samarth Deepti, FDA/CDER; Chekka Lakshmi Manasa, FDA/CDER; Mohammed Esraa, FDA/CDER; Decker Erica; Guo Yan; Wheeler Will, IMS Inc.; Howard Kristina, FDA/CDER; Schrieber Sarah J; Florian Jeffey FDA/CDER; Wang Yow-Ming, FDA/CDER; Strauss David G, FDA/CDER, Hyland Paula L, FDA/CDER	Deepti.Samarth@fda.hhs.gov
	Lysophosphatidylcholine mediates neutrophil activity through early metabolic modulation following immunization with a live-attenuated Leishmania vaccine	Hannah L Markle, FDA/CBER/OBRR/DETTD/LEP; Thalia Pacheco-Fernandez, FDA/CBER/OBRR/DETTD/LEP, Parna Bhattacharya, FDA/OHT7/CDRH; Jinchun Sun, FDA/NCTR; Nazli Azodi, FDA/CBER/OBRR/DETTD/LEP; Grace Kitthanawong, FDA/CBER/OBRR/DETTD/LEP; Caroline Hobson, FDA/CBER/OBRR/DETTD/LEP; Richard Beger, FDA/NCTR; Sreenivas Gannavaram, FDA/CBER/OBRR/DETTD/LEP, Hira Nakhasi, FDA/CBER/OBRR/DETTD/LEP	Hannah.Markle@fda.hhs.gov
	A New Generation of Reference Materials to Promote High Quality Data in Untargeted Metabolomics	Amanda Bayless, NIST/CSD; Clay Davis, NIST/CSD; Fabio Casu, NIST/CSD; Tracey Schock, NIST/CSD	Amanda.bayless@nist.gov
	High resolution MALDI imaging mass spectrometry to assess spatial lipidomics of mouse fetal neural tube defects after maternal opioid exposure	Dustyn Barnette, FDA/NCTR, E. Ellen Jones, FDA/NCTR, Pravin Kaldhone, FDA/CBER, Grace Lee, FDA/CDER, Kelly Davis, FDA/NCTR, Sumit Sarkar, FDA/NCTR, Pritpal Malhi, FDA/CDER, J. Edward Fisher, FDA/CDER, Joseph P. Hanig, FDA/CDER, Richard D. Beger, FDA/NCTR, Richard D. Mellon, FDA/CDER, Amy L. Inselman, FDA/NCTR	Dustyn.Barnette@fda.hhs.gov
	Implementing a high-throughput nanoflow proteomics workflow using a dual-trap single column approach with in-plate resuspension of peptides	Benjamin Neely, NIST; W. Clay Davis, NIST	benjamin.neely@nist.gov
Data integration and data management
	Fostering Public Health Bioinformatics and Collaboration with GalaxyTrakr	Jayanthi Gangiredla, FDA/CFSAN; Hugh Rand, FDA/CFSAN; Daniel Benisatto, DRT Strategies; Justin Payne, FDA/CFSAN; Charles Strittmatter, FDA/CFSAN; Jimmy Sanders, SDS Solutions, Inc.; William J. Wolfgang, New York State Department of Health/Wadsworth Center; Kevin Libuit, Division of Consolidated Laboratory Services/Department of General Services; James Herrick, James Madison University/Biology Department ; Melanie Prarat, Ohio Department of Agriculture/Animal Disease Diagnostic Laboratory; Magaly Toro, Universidad de Chile/Laboratorio de Microbiología y Probióticos; Thomas Farrell, FDA/CFSAN; James Pettengill, FDA/CFSAN; Errol Strain, FDA/CFSAN;	Jayanthi.Gangiredla@fda.hhs.gov
	Impact of FDA’s Low- or No-Cost Tech-Enabled Traceability Challenge on Strengthening Traceback Investigations	Tanya Gupta, FDA/CFSAN/OCORE; Jorge Hurtado Maturana, FDA/CFSAN/OCORE; Sharon Seelman, FDA/CFSAN/OCORE; Adam Friedlander, FDA/CFSAN/OCORE; CAPT Kari Irvin, FDA/CFSAN/OCORE	Tanya.Gupta@fda.hhs.gov