Veterinary Laboratory Investigation and Response Network (Vet-LIRN)

Biography

Dave Rotstein received his bachelor’s degree from the Florida State University and his veterinary degree from the University of Florida. After a few years in practice including wildlife work, he completed a master’s degree from the University of Florida, where he investigated alligator microsatellite DNA as an indicator of early embryonic mortality from environmentally impacted lakes. He completed his residency in veterinary pathology at the University of Florida and North Carolina State University. At the North Carolina State University, he obtained his veterinary pathology boards and joined the faculty; his research focuses included marine mammals and wildlife. He was a faculty member at the University of Tennessee College of Veterinary Medicine with a primary focus on marine mammals. In 2010, Dr. Rostein moved to the DC area and joined FDA as a reviewer for the Aquatics Drug Team. He then served on a response team for FDA’s Coordinated Outbreak and Response Network. He is now the Veterinary Laboratory Investigation and Response Network (Vet-LIRN) liaison to CVM’s Division of Compliance’s Complaint Emergency Recall Team (CERT).

Research

Dr. Rotstein provides veterinary pathology support to Vet-LIRN and other FDA offices as needed. Current and past activities include cardiac assessment of dogs with dilated cardiomyopathy, histologic evaluation of pet food for product components, and evaluation of intestinal effects of anthrax.

Select Publications

Jones JL, Wang L, Ceric O, Nemser SM, Rotstein DS, Jurkovic DA, Rosa Y, Byrum B, Cui J, Zhang Y, Brown CA, Burnum AL, Sanchez S, Reimschuessel R. 2019. Whole genome sequencing confirms source of pathogens associated with bacterial foodborne illness in pets fed raw pet food. J Vet Diagn Invest. 31:235-240

Jones J, Ceric O, Nemser S, Rotstein D, Reimschuessel R. 2018. Information for veterinarians on reporting suspected animal food issues. JAVMA 253: 550-553.

Endo Y, Takeda K, Mohan N, Shen Y, Jiang J, Rotstein D, Wu WJ. 2018.Payload of T-DM1 binds to cell surface cytoskeleton-associated protein 5 to mediate cytotoxicity of hepatocytes. Oncotarget. 2018 9:37200-37215.

Huang, B, Xie T, Rotstein D, Fang H, Frucht DM. 2015. Passive immunotherapy provides post-exposure prophylaxis against enteric invasion and lethal sepsis in a murine model of gastrointestinal anthrax infection. Toxins (Basel) 7: 3960-3976.

Collier MG, Khudyakov Y, Selvage D, Cameron MA, Epson E, Cronquist A, Jervis R, Lamba K, Kimura A, Sowadsky R, Hassan R, Park SY,Garza E, Rotstein D, Lance S, Hill T, Wise M, Nelson NP, Suryaprasad A, Drobeniuc J, Holmberg S, Xue F. 2014. Multistate outbreak of Hepatitis A associated with frozen pomegranate arils imported from Turkey. Lancet Infect Dis 14: 976-981.

Hunt A, Bohm SR, Bidol SA, Achen M, Cui J, Denny L, Brandt E, Davis S, Woody D, Reimschuessel R, Tuite C, Rotstein D, Schwensoh C, Behravesh CB, Imanishi M. 2012. Notes from the field: Human Salmonella Infantis infections linked to dry dog food-United States and Canada, 2012. MMWR 23: 436.