You will notice some delay the first time you run EDKB because the entire EDKB application must download the first time you access it. Because future uses of the software will only download any parts of the application that have been changed, the application should start much quicker. You may also be prompted to update your version of Java before EDKB will run. *Note: Use this link to install or re-install Java. 

Register for updates by contacting [email protected].

Possible Error Messages

• "Connection failed: the network adapter could not establish the connection..."
  
  This might be due to your organization's firewall. Many firewalls are set up to only allow traffic to destination port 80 on remote hosts (Web traffic). However, the EDKB server needs to be contacted on port 1610. Thus, you need to contact your system administrator about this particular port number (port 1610) that may need to be opened as an allowed destination port for outgoing connections on your organization's firewall. 
  
  The following statement has been prepared for your convenience to communicate with your system administrator: 
  
  "The EDKB server edkb.fda.gov is listening on port 1610 for connections from the EDKB client software. An organization whose hosts are to run the EDKB client software needs to allow outgoing connections from any port (source port is randomly chosen on the client as is usual with Internet communications), to the fixed destination port of 1610 on edkb.fda.gov

Contact Information

Please address any questions and suggestions to Dr. Weida Tong at 870-543-7142 or [email protected].

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EDKB is a product designed and produced by the National Center for Toxicological Research (NCTR).  FDA and NCTR retain ownership of this product.

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Resources For You

• About the National Center for Toxicological Research
• Bioinformatics Tools
• Estrogenic Activity Database (EADB)