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  1. Development Resources

Ceftolozane Tazobactam – Injection products

Recognized Interpretive Criteria

 

Minimum Inhibitory
Concentrations

(mcg/mL)

Disk Diffusion
(zone diameter in mm)

Pathogen

S

I

R

S

I

R

Enterobacterales

M-100 standard is recognized

Pseudomonas aeruginosa

M-100 standard is recognized

Streptococcus spp Viridans
Group

M-100 standard is recognized

-

-

-

Bacteroides fragilis

≤8/4

16/4

≥32/4

-

-

-

Haemophilus influenzae

M-100 standard is recognized

-

-

-

S = Susceptible; I = Intermediate; R = Resistant

STIC are based on a dose for adults of 1.5g every 8 h for the treatment of complicated intra-abdominal infections and complicated urinary tract infections or a dose of 3 g every 8 h for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.

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