O. Alberto Chiesa DVM, MS, PhD.
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Division of Applied Veterinary Research
Biography
Alberto Chiesa obtained his DVM degree from the University of Buenos Aires’ Faculty of Veterinary Medicine in 1974. He was in private practice as an equine veterinarian in Argentina, Spain, and France until 1999. Dr. Chiesa earned his MS from the University of Barcelona Faculty of Veterinary Medicine’s Department of Animal Medicine and Surgery in 1995, and a PhD in clinical pathology in 1999. He began his career in regulatory research as a post-doctoral fellow as part of the Division of Residue Chemistry in the Office of Research at the Center of Veterinary Medicine from 2001 to 2005. In 2006, he joined the Laboratory of Cardiovascular and Interventional Therapeutics, Office of Science and Engineering Laboratories, at the FDA’s Center for Devices and Radiologic Health. Dr. Chiesa returned to CVM’s Office of Research in 2010 as a supervisory veterinary medical officer and currently serves as their clinical veterinarian.
Research
Dr. Chiesa’s research specializations include the development of large-animal models, minimally invasive surgical techniques, and image-guided procedures. His minimally invasive techniques are applied to obtain serial tissue samples in food animals for pharmacokinetic studies. His main interest is to reduce the number of animals required to answer regulatory questions and to refine techniques to perform research studies in food animals. Dr. Chiesa’s work has been presented in national and international meetings and published in peer-reviewed journals.
Select Publications
Chiesa, O. A., Heller, D. N., Karanian, J. W., Pritchard, W. F., Lopez, M., Smith, S., Kijak, P. J., Ward, J. L., von Bredow, J., Myers, M. J. Inhalation anesthesia induced by isofluorane alters penicillin disposition in swine tissues (2017). J Veterinary Pharmacology & Therapeutics. 40(4):356-362.
Chiesa, O.A., Feng, S., Kijak P., Smith, E.A., Li, H., Qiu, J. Plasma pharmacokinetics of ceftiofur metabolite desfuroylceftiofur cysteine disulfide in Holstein steers: Application of nonlinear mixed-effects modeling. (2016) J Veterinary Pharmacology & Therapeutics. 39(2):149–56.
Chiesa, O.A., Idowu, O.R., Heller, D., Smith, M., Nochetto, C., Chamberlain, P.L., Gehring, R., von Bredow, J. A. Holstein cow-calf model for the transfer of ciprofloxacin through milk after a long-term intravenous infusion. (2013) J Veterinary Pharmacology & Therapeutics. 36(5):425–33.
Chiesa, O.A., Li, H., Kijak, P,J,, Li, J.X., Lancaster, V., Smith, M.L., Heller, D.N., Thomas, M.H., von Bredow, J. Tissue/fluid correlation study for the depletion of sulfadimethoxine in bovine kidney, liver, plasma, urine, and oral fluid. (2012) J Veterinary Pharmacology & Therapeutics. 35(3):249–58.
Chiesa, O.A., von Bredow J., Li, H., Smith M. Isobaric (gasless) laparoscopic liver and kidney biopsy in standing steers. (2009) Canadian J Veterinary Research. 73(1):42–8.
Chiesa, O.A., von Bredow, J., Smith, M., Thomas, M. One-port video assisted laparoscopic kidney biopsy in standing steers. (2009) Res Vet Sci. 87(1):133–4.
Chiesa, O.A., von Bredow, J., Smith, M., Heller, D., Condon, R., Thomas, M. Bovine kidney tissue/biological fluid correlation for penicillin. (2006) J Veterinary Pharmacology & Therapeutics. 29(4):299–306.
Heller, D.N., Smith, M.L., Chiesa OA. LC/MS/MS measurement of penicillin G in bovine plasma, urine, and biopsy samples taken from kidneys of standing animals (2016). J Chromatogr B Analyt Technol Biomed Life Sci. 2;830(1):91-9
Chiesa, O.A., Cullison, R., Anderson, D.E., Moulton, K., Galuppo, L.D., von Bredow, J. Development of a technique for serial bilateral renal biopsy in steers. (2006) Canadian J Veterinary Research. 70(2):87–93.
Chiesa, O.A., von Bredow, J., Heller, D., Nochetto, C., Smith, M., Moulton, K., Thomas, M. Use of tissue-fluid correlations to estimate gentamicin residues in kidney tissue of Holstein steers. (2006) J Veterinary Pharmacology & Therapeutics. 29(2):99–106.
- Contact Information
- O. Alberto Chiesa
- +1 (240) 402-0926