Minimum Inhibitory Concentrations (mcg/mL)				Disk Diffusion b (zone diameter in mm)
Pathogen	S	SDD	I	R	S	SDD	I	R
Enterobacterales a,c	≤8/8	-	-	≥16/8	≥21	-	-	≤20
Pseudomonas aeruginosa a	≤8/8	-	-	≥16/8	≥18	-	-	≤17

S = Susceptible; SDD= susceptible-dose dependent; I = Intermediate; R = Resistant

1. Susceptibility interpretive criteria are based on a dose of 2 grams cefepime and 0.5 g enmetazobactam every 8 hours by intravenous infusion over 2 hours in patients with an estimated glomerular filtration rate from 60 mL/min to less than 130 mL/min.
2. For disk diffusion, use paper disks impregnated with 30/20 mcg cefepime/enmetazobactam.
3. Among Enterobacterales species, clinical efficacy was shown for Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Enterobacter cloacae complex.