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In this section: Search for FDA Guidance Documents

Withdrawn or Expired Clinical Trial Guidance Documents

This table lists clinical trial guidance documents that have been withdrawn and no longer represent FDA’s current thinking. These documents are presented for historical purposes only.

Title	Issue Date	Withdrawal Date
Clinical Investigator Regulatory Sanctions - Information Sheet	January 1998	October 2023
Charging for Investigational Products: Guidance for Institutional Review Boards and Clinical Investigators	January 1998	October 2023
Drug Study Designs: Guidance for Institutional Review Boards and Clinical Investigators	January 1998	October 2023
Treatment Use of Investigational Drugs: Guidance for Institutional Review Boards and Clinical Investigators	January 1998	October 2023

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