Skip to main content

High-Risk

NIH Common Fund: 10 Years of Transformative Science

Posted on by Dr. Francis Collins

Common Fund 10th Anniversary LogoHappy 10th Anniversary to the Common Fund! It’s hard to believe that it’s been a decade since I joined then-NIH Director Elias Zerhouni at the National Press Club to launch this trans-NIH effort to catalyze innovation and speed progress across many fields of biomedical research.

We’re marking this milestone with a special celebration today at NIH’s main campus. And, for those of you who can’t make it to Bethesda to join in the festivities, you can watch the videocast (live or archived). But allow me also to take this opportunity to share just a bit of the history and a few of the many achievements of this bold new approach to the support of science.


Creative Minds: Lighting Up Memory

Posted on by Dr. Francis Collins

Christine Denny, Columbia UniversityOne of the most debilitating, and heartbreaking, consequences of Alzheimer’s disease is the way it slowly robs people of their memories. Unfortunately, we don’t yet have a cure for Alzheimer’s, let alone a good understanding of exactly how this disease destroys memory skills. That’s why, in this first post in my series highlighting some of the awardees in NIH Common Fund’s High-Risk, High-Reward Research Program, I’m excited to introduce a young scientist who’s using some cool technology to tackle this formidable challenge: Christine Ann Denny.

A winner of a 2013 NIH Director’s Early Independence Awards (often called the “skip-the-postdoc” award), Denny has developed a technique to label the cells that encode individual memories in the brains of mice. That’s right: she tags the nerve cells that build these memories, the neurons, with a fluorescent molecule that glows.