Genomic variations can affect a patient’s risk for cancer, response to medications, and numerous other vital health outcomes. In fact, nine of the ten leading causes of death in the U.S. are influenced by genomic factors. The need for systems that help clinicians integrate genomics into care decisions has grown in importance.  
Recognizing this need, in 2017 ONC launched Sync for Genes, a project that sought to advance standards and tools to effectively integrate genomic information into clinical workflows.